Category Science & Ingredients

Mechanism Overview: From Gut Microbiome to Hair Follicle The concept of a “gut-skin axis” has gained significant attention in dermatology…

Mechanism Overview: BMP as the Brake on Hair Growth Bone morphogenetic proteins (BMPs) are members of the TGF-β superfamily that…

Mechanism Overview: The Molecular Architecture of Hair Hair is composed of approximately 95% keratin—a family of fibrous structural proteins that…

Mechanism Overview: Selenium and the Selenoprotein Family Selenium is an essential trace element that is incorporated as the amino acid…

Mechanism Overview: Caffeine as a Follicle Stimulant Caffeine (1,3,7-trimethylxanthine) is the most widely consumed psychoactive substance in the world, and…

Mechanism Overview: Inflammation as a Driver of Follicle Dysfunction Inflammation in the hair follicle is not always visible to the…

Mechanism Overview: Blood Supply as a Growth Limiting Factor Vascular endothelial growth factor (VEGF) is the master regulator of blood…

Mechanism Overview: A Natural 5-Alpha-Reductase Inhibitor? Saw palmetto (Serenoa repens) is a small palm native to the southeastern United States…

Mechanism Overview: Peppermint Oil’s Surprising Follicular Effects Peppermint oil (Mentha piperita) is one of the most widely discussed natural remedies…

Mechanism Overview: The Hormonal Orchestra That Controls Hair Hair follicles are exquisitely sensitive to hormonal signals. They express receptors for…

Mechanism Overview: More Than an Antifungal Ketoconazole is a synthetic imidazole antifungal agent that has been used for decades to…

Mechanism Overview: Stem Cells as the Follicle’s Renewal Engine Hair follicles are unique among mammalian organs in their ability to…